Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2
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چکیده
منابع مشابه
Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2.
AIMS Statins have beneficial vascular effects beyond their cholesterol-lowering action. Since macrophages play a central role in atherogenesis, we characterized the effects of simvastatin on gene expression profile of human peripheral blood monocyte (HPBM)-macrophages. METHODS AND RESULTS Gene expression profile was studied using Affymetrix gene chip analysis. Lentiviral gene transfer of Krup...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2008
ISSN: 1755-3245,0008-6363
DOI: 10.1093/cvr/cvn007